Multi-enzyme catalysed processes using purified and whole-cell biocatalysts towards a 1,3,4-substituted tetrahydroisoquinoline

In this work, two multi-enzyme catalysed processes to access a 1,3,4-substituted tetrahydroisoquinoline (THIQ), using either purified enzymes or lyophilised whole-cell catalysts, are presented. A key focus was the first step in which the reduction of 3-hydroxybenzoic acid (3-OH-BZ) into 3-hydroxyben...

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Detalles Bibliográficos
Autores principales: Weber, Douglas, de Souza Bastos, Lucas, Winkler, Margit, Ni, Yeke, Aliev, Abil E., Hailes, Helen C., Rother, Doerte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053099/
https://www.ncbi.nlm.nih.gov/pubmed/37006360
http://dx.doi.org/10.1039/d3ra01210g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053099/
https://www.ncbi.nlm.nih.gov/pubmed/37006360
http://dx.doi.org/10.1039/d3ra01210g

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