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Prolonged Alprazolam Treatment Alters Components of Glutamatergic Neurotransmission in the Hippocampus of Male Wistar Rats—The Neuroadaptive Changes following Long-Term Benzodiazepine (Mis)Use

Alprazolam (ALP), a benzodiazepine (BDZ) used to treat anxiety, panic, and sleep disorders, is one of the most prescribed psychotropic drugs worldwide. The side effects associated with long-term (mis)use of ALP have become a major challenge in pharmacotherapy, emphasizing the unmet need to further i...

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Detalles Bibliográficos
Autores principales: Zaric Kontic, Marina, Dragic, Milorad, Martinovic, Jelena, Mihajlovic, Katarina, Brkic, Zeljka, Mitrovic, Natasa, Grkovic, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053378/
https://www.ncbi.nlm.nih.gov/pubmed/36986431
http://dx.doi.org/10.3390/ph16030331