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Evolutionary relevance of single nucleotide variants within the forebrain exclusive human accelerated enhancer regions
BACKGROUND: Human accelerated regions (HARs) are short conserved genomic sequences that have acquired significantly more nucleotide substitutions than expected in the human lineage after divergence from chimpanzees. The fast evolution of HARs may reflect their roles in the origin of human-specific t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053400/ https://www.ncbi.nlm.nih.gov/pubmed/36991330 http://dx.doi.org/10.1186/s12860-023-00474-5 |