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Evolutionary relevance of single nucleotide variants within the forebrain exclusive human accelerated enhancer regions

BACKGROUND: Human accelerated regions (HARs) are short conserved genomic sequences that have acquired significantly more nucleotide substitutions than expected in the human lineage after divergence from chimpanzees. The fast evolution of HARs may reflect their roles in the origin of human-specific t...

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Detalles Bibliográficos
Autores principales: Khatoon, Hizran, Raza, Rabail Zehra, Saleem, Shoaib, Batool, Fatima, Arshad, Saba, Abrar, Muhammad, Ali, Shahid, Hussain, Irfan, Shubin, Neil H., Abbasi, Amir Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053400/
https://www.ncbi.nlm.nih.gov/pubmed/36991330
http://dx.doi.org/10.1186/s12860-023-00474-5

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