Reduced replication but increased interferon resistance of SARS-CoV-2 Omicron BA.1

The IFN system constitutes a powerful antiviral defense machinery. Consequently, effective IFN responses protect against severe COVID-19 and exogenous IFNs inhibit SARS-CoV-2 in vitro. However, emerging SARS-CoV-2 variants of concern (VOCs) may have evolved reduced IFN sensitivity. Here, we determin...

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Detalles Bibliográficos
Autores principales: Nchioua, Rayhane, Schundner, Annika, Klute, Susanne, Koepke, Lennart, Hirschenberger, Maximilian, Noettger, Sabrina, Fois, Giorgio, Zech, Fabian, Graf, Alexander, Krebs, Stefan, Braubach, Peter, Blum, Helmut, Stenger, Steffen, Kmiec, Dorota, Frick, Manfred, Kirchhoff, Frank, Sparrer, Konstantin MJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053418/
https://www.ncbi.nlm.nih.gov/pubmed/36977594
http://dx.doi.org/10.26508/lsa.202201745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053418/
https://www.ncbi.nlm.nih.gov/pubmed/36977594
http://dx.doi.org/10.26508/lsa.202201745

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