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Amphiphilic Cell-Penetrating Peptides Containing Arginine and Hydrophobic Residues as Protein Delivery Agents

The entry of proteins through the cell membrane is challenging, thus limiting their use as potential therapeutics. Seven cell-penetrating peptides, designed in our laboratory, were evaluated for the delivery of proteins. Fmoc solid-phase peptide synthesis was utilized for the synthesis of seven cycl...

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Detalles Bibliográficos
Autores principales: Moreno, Jonathan, Zoghebi, Khalid, Salehi, David, Kim, Lois, Shoushtari, Sorour Khayyatnejad, Tiwari, Rakesh K., Parang, Keykavous
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053436/
https://www.ncbi.nlm.nih.gov/pubmed/36986567
http://dx.doi.org/10.3390/ph16030469