Semi-Synthesis and Biological Evaluation of 25(R)-26-Acetoxy-3β,5α-Dihydroxycholest-6-One

Previously, we identified a series of steroids (1–6) that showed potent anti-virus activities against respiratory syncytial virus (RSV), with IC(50) values ranging from 3.23 to 0.19 µM. In this work, we first semi-synthesized and characterized the single isomer of 5, 25(R)-26-acetoxy-3β,5α-dihydroxy...

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Detalles Bibliográficos
Autores principales: Maimaitiming, Mireguli, Lv, Ling, Zhang, Xuetao, Xia, Shuli, Li, Xin, Wang, Pingyuan, Liu, Zhiqing, Wang, Chang-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053440/
https://www.ncbi.nlm.nih.gov/pubmed/36976240
http://dx.doi.org/10.3390/md21030191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053440/
https://www.ncbi.nlm.nih.gov/pubmed/36976240
http://dx.doi.org/10.3390/md21030191

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