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StaR Is a Positive Regulator of Topoisomerase I Activity Involved in Supercoiling Maintenance in Streptococcus pneumoniae

The DNA topoisomerases gyrase and topoisomerase I as well as the nucleoid-associated protein HU maintain supercoiling levels in Streptococcus pneumoniae, a main human pathogen. Here, we characterized, for the first time, a topoisomerase I regulator protein (StaR). In the presence of sub-inhibitory n...

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Detalles Bibliográficos
Autores principales: de Vasconcelos Junior, Antonio A., Tirado-Vélez, Jose M., Martín-Galiano, Antonio J., Megias, Diego, Ferrándiz, María-José, Hernández, Pablo, Amblar, Mónica, de la Campa, Adela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053502/
https://www.ncbi.nlm.nih.gov/pubmed/36983048
http://dx.doi.org/10.3390/ijms24065973