Cadmium Disrupted ER Ca(2+) Homeostasis by Inhibiting SERCA2 Expression and Activity to Induce Apoptosis in Renal Proximal Tubular Cells

Cadmium (Cd(2+)) exposure induces chronic kidney disease and renal cancers, which originate from injury and cancerization of renal tubular cells. Previous studies have shown that Cd(2+) induced cytotoxicity by disrupting the intracellular Ca(2+) homeostasis that is physically regulated by the endopl...

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Detalles Bibliográficos
Autores principales: Li, Kongdong, Guo, Chuanzhi, Ruan, Jiacheng, Ning, Bo, Wong, Chris Kong-Chu, Shi, Haifeng, Gu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053525/
https://www.ncbi.nlm.nih.gov/pubmed/36983052
http://dx.doi.org/10.3390/ijms24065979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053525/
https://www.ncbi.nlm.nih.gov/pubmed/36983052
http://dx.doi.org/10.3390/ijms24065979

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