Changes in Memory, Sedation, and Receptor Kinetics Imparted by the β2-N265M and β3-N265M GABA(A) Receptor Point Mutations

Point mutations in the β2 (N265S) and β3 (N265M) subunits of γ-amino butyric acid type A receptors (GABA(A)Rs) that render them insensitive to the general anesthetics etomidate and propofol have been used to link modulation of β2-GABA(A)Rs to sedation and β3-GABA(A)Rs to surgical immobility. These m...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdulzahir, Alifayaz, Klein, Steven, Lor, Chong, Perkins, Mark G., Frelka, Alyssa, Pearce, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053577/
https://www.ncbi.nlm.nih.gov/pubmed/36982709
http://dx.doi.org/10.3390/ijms24065637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053577/
https://www.ncbi.nlm.nih.gov/pubmed/36982709
http://dx.doi.org/10.3390/ijms24065637

Ejemplares similares