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Changes in Memory, Sedation, and Receptor Kinetics Imparted by the β2-N265M and β3-N265M GABA(A) Receptor Point Mutations
Point mutations in the β2 (N265S) and β3 (N265M) subunits of γ-amino butyric acid type A receptors (GABA(A)Rs) that render them insensitive to the general anesthetics etomidate and propofol have been used to link modulation of β2-GABA(A)Rs to sedation and β3-GABA(A)Rs to surgical immobility. These m...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053577/ https://www.ncbi.nlm.nih.gov/pubmed/36982709 http://dx.doi.org/10.3390/ijms24065637 |