Changes in Plasma Metabolic Signature upon Acute and Chronic Morphine Administration in Morphine-Tolerant Mice

Morphine administration causes system-level metabolic changes. Here, we show that morphine-tolerant mice exhibited distinct plasma metabolic signatures upon acute and chronic administration. We utilized a mouse model of morphine tolerance by exposing mice to increasing doses of the drug over 4 days....

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Detalles Bibliográficos
Autores principales: Kutchy, Naseer A., Palermo, Amelia, Ma, Rong, Li, Zhong, Ulanov, Alexandria, Callen, Shannon, Siuzdak, Gary, Roy, Sabita, Buch, Shilpa, Hu, Guoku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053579/
https://www.ncbi.nlm.nih.gov/pubmed/36984873
http://dx.doi.org/10.3390/metabo13030434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053579/
https://www.ncbi.nlm.nih.gov/pubmed/36984873
http://dx.doi.org/10.3390/metabo13030434

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