Parthenolide Phytosomes Attenuated Gentamicin-Induced Nephrotoxicity in Rats via Activation of Sirt-1, Nrf2, OH-1, and NQO1 Axis

Nephrotoxicity is a serious complication that limits the clinical use of gentamicin (GEN). Parthenolide (PTL) is a sesquiterpene lactone derived from feverfew with various therapeutic benefits. However, PTL possesses low oral bioavailability. This study aimed to evaluate the therapeutic protective e...

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Detalles Bibliográficos
Autores principales: Albalawi, Rawan S., Binmahfouz, Lenah S., Hareeri, Rawan H., Shaik, Rasheed A., Bagher, Amina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053629/
https://www.ncbi.nlm.nih.gov/pubmed/36985711
http://dx.doi.org/10.3390/molecules28062741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053629/
https://www.ncbi.nlm.nih.gov/pubmed/36985711
http://dx.doi.org/10.3390/molecules28062741

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