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Mind the mechanical strength: tailoring a 3D matrix to encapsulate isolated human preantral follicles

STUDY QUESTION: Would a hydrogel with similar mechanical properties to the human ovarian cortex support preantral follicle development? SUMMARY ANSWER: Yes, our tailored PEGylated fibrin hydrogel was shown to significantly improve follicle growth in vitro. WHAT IS KNOWN ALREADY: One of the main chal...

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Detalles Bibliográficos
Autores principales: Dadashzadeh, Arezoo, Moghassemi, Saeid, Peaucelle, Alexis, Lucci, Carolina M, Amorim, Christiani A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053646/
https://www.ncbi.nlm.nih.gov/pubmed/37009395
http://dx.doi.org/10.1093/hropen/hoad004