Synthesis of 3-substituted 2,3-dihydropyrazino[1,2-a]indol-4(1H)-ones by sequential reactions of 2-indolylmethyl acetates with α-amino acids

The synthesis of 2,3-dihydropyrazino[1,2-a]indol-4(1H)-ones from the sequential reaction of amino acid methyl esters with readily available indole-2-ylmethyl acetates is described. The reaction proceeds in situ under basic conditions of highly unstable and reactive 2-alkylideneindolenines followed b...

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Detalles Bibliográficos
Autores principales: Goggiamani, Antonella, Arcadi, Antonio, Ciogli, Alessia, De Angelis, Martina, Dessalvi, Stefano, Fabrizi, Giancarlo, Iavarone, Federica, Iazzetti, Antonia, Sferrazza, Alessio, Zoppoli, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053697/
https://www.ncbi.nlm.nih.gov/pubmed/37006346
http://dx.doi.org/10.1039/d3ra01335a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053697/
https://www.ncbi.nlm.nih.gov/pubmed/37006346
http://dx.doi.org/10.1039/d3ra01335a

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