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Influence of Lipidation Pattern of the KR12 Fragment of Peptide LL-37 on Its Antibacterial and Hemolytic Activities

Contemporary medicine has been confronted by multidrug resistance. Therefore, new antibiotics are sought to alleviate the problem. In this study, we estimated the effect of the positioning and extent of lipidation (mainly octanoic acid residue) in the KR12-NH(2) molecule on antibacterial and hemolyt...

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Detalles Bibliográficos
Autores principales: Kamysz, Elżbieta, Sikorska, Emilia, Bauer, Marta, Sikora, Karol, Neubauer, Damian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053710/
https://www.ncbi.nlm.nih.gov/pubmed/36982579
http://dx.doi.org/10.3390/ijms24065505