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CDDO-Me Abrogates Aberrant Mitochondrial Elongation in Clasmatodendritic Degeneration by Regulating NF-κB-PDI-Mediated S-Nitrosylation of DRP1

Clasmatodendrosis is a kind of astroglial degeneration pattern which facilitates excessive autophagy. Although abnormal mitochondrial elongation is relevant to this astroglial degeneration, the underlying mechanisms of aberrant mitochondrial dynamics are still incompletely understood. Protein disulf...

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Detalles Bibliográficos
Autores principales: Lee, Duk-Shin, Kim, Tae-Hyun, Park, Hana, Kim, Ji-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053800/
https://www.ncbi.nlm.nih.gov/pubmed/36982949
http://dx.doi.org/10.3390/ijms24065875