Characterization of Human Norovirus Nonstructural Protein NS1.2 Involved in the Induction of the Filamentous Endoplasmic Reticulum, Enlarged Lipid Droplets, LC3 Recruitment, and Interaction with NTPase and NS4

Human noroviruses (HuNVs) are the leading cause of gastroenteritis worldwide. NS1.2 is critical for HuNV pathogenesis, but the function is still unclear. The GII NS1.2 of HuNVs, unlike GI NS1.2, was localized to the endoplasmic reticulum (ER) and lipid droplets (LDs) and is accompanied by a distorte...

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Detalles Bibliográficos
Autores principales: Hung, Chien-Hui, Yen, Ju-Bei, Chang, Pey-Jium, Chen, Lee-Wen, Huang, Tsung-Yu, Tsai, Wan-Ju, Tsai, Yu-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053803/
https://www.ncbi.nlm.nih.gov/pubmed/36992520
http://dx.doi.org/10.3390/v15030812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053803/
https://www.ncbi.nlm.nih.gov/pubmed/36992520
http://dx.doi.org/10.3390/v15030812

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