Natural Lipid Extracts as an Artificial Membrane for Drug Permeability Assay: In Vitro and In Silico Characterization

In vitro non-cellular permeability models such as the parallel artificial membrane permeability assay (PAMPA) are widely applied tools for early-phase drug candidate screening. In addition to the commonly used porcine brain polar lipid extract for modeling the blood–brain barrier’s permeability, the...

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Detalles Bibliográficos
Autores principales: Vincze, Anna, Dékány, Gergely, Bicsak, Richárd, Formanek, András, Moreau, Yves, Koplányi, Gábor, Takács, Gergely, Katona, Gábor, Balogh-Weiser, Diána, Arany, Ádám, Balogh, György T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053807/
https://www.ncbi.nlm.nih.gov/pubmed/36986760
http://dx.doi.org/10.3390/pharmaceutics15030899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053807/
https://www.ncbi.nlm.nih.gov/pubmed/36986760
http://dx.doi.org/10.3390/pharmaceutics15030899

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