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Asymmetric Organocatalytic Mannich Reaction in the Synthesis of Hybrid Isoindolinone-Pyrazole and Isoindolinone-Aminal from Functionalized α-Amidosulfone

The investigation of the reactivity of an α-amido sulfone derived from 2-formyl benzoate under organocatalytic conditions in the presence of acetylacetone allowed the synthesis of a new heterocyclic hybrid isoindolinone-pyrazole with high enantiomeric excess. Dibenzylamine was also used as a nucleop...

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Detalles Bibliográficos
Autores principales: Di Mola, Antonia, De Piano, Felice, Serusi, Lorenzo, Pierri, Giovanni, Palombi, Laura, Massa, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053823/
https://www.ncbi.nlm.nih.gov/pubmed/36982854
http://dx.doi.org/10.3390/ijms24065783