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[(111)In]In/[(177)Lu]Lu-AAZTA(5)-LM4 SST(2)R-Antagonists in Cancer Theranostics: From Preclinical Testing to First Patient Results

Aiming to expand the application of the SST(2)R-antagonist LM4 (DPhe-c[DCys-4Pal-DAph(Cbm)-Lys-Thr-Cys]-DTyr-NH(2)) beyond [(68)Ga]Ga-DATA(5m)-LM4 PET/CT (DATA(5m), (6-pentanoic acid)-6-(amino)methy-1,4-diazepinetriacetate), we now introduce AAZTA(5)-LM4 (AAZTA(5), 1,4-bis(carboxymethyl)-6-[bis(carb...

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Detalles Bibliográficos
Autores principales: Nock, Berthold A., Kanellopoulos, Panagiotis, Moon, Euy Sung, Rouchota, Maritina, Loudos, George, Ballal, Sanjana, Yadav, Madhav P., Bal, Chandrasekhar, Mishra, Prashant, Sheokand, Parvind, Roesch, Frank, Maina, Theodosia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053881/
https://www.ncbi.nlm.nih.gov/pubmed/36986637
http://dx.doi.org/10.3390/pharmaceutics15030776