Cargando…

Effect of Dexamethasone on Abiraterone Pharmacokinetics in Mice: Determined by LC/MS Analysis

Background: Abiraterone acetate is a cytochrome P450 17A1 (CYP17A1) inhibitor that is indicated for use in both castration-resistant and castration-sensitive prostate cancer patients. To manage the mineralocorticoid effects of CYP17A1 inhibition, a glucocorticoid such as dexamethasone is co-administ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deb, Subrata, Ben-Eltriki, Mohamed, Adomat, Hans, Chin, Mei Y., Tomlinson Guns, Emma S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053955/ https://www.ncbi.nlm.nih.gov/pubmed/36976310 http://dx.doi.org/10.3390/medicines10030021

Ejemplares similares

Calcitriol in Combination Therapy for Prostate Cancer: Pharmacokinetic and Pharmacodynamic Interactions
por: Ben-Eltriki, Mohamed, et al.
Publicado: (2016)

Anti-Tumor Effects of Ginsenoside 20(S)-Protopanaxadiol and 1,25-Dihydroxyvitamin D3 Combination in Castration Resistant Prostate Cancer
por: Ben-Eltriki, Mohamed, et al.
Publicado: (2021)

Steroidogenesis in Peripheral and Transition Zones of Human Prostate Cancer Tissue
por: Deb, Subrata, et al.
Publicado: (2021)

Characterization of Precursor-Dependent Steroidogenesis in Human Prostate Cancer Models
por: Deb, Subrata, et al.
Publicado: (2018)

20(S)-protopanaxadiol regio-selectively targets androgen receptor: anticancer effects in castration-resistant prostate tumors
por: Ben-Eltriki, Mohamed, et al.
Publicado: (2018)

Simultaneous Determination of Moxifloxacin Hydrochloride and Dexamethasone Sodium Phosphate in Rabbit Ocular Tissues and Plasma by LC-MS/MS: Application for Pharmacokinetics Studies
por: Zhao, Xinxin, et al.
Publicado: (2022)

Determination and pharmacokinetics study of oxyclozanide suspension in cattle by LC-MS/MS
por: Zhang, Jili, et al.
Publicado: (2019)

Determination and pharmacokinetics study of UK-5099 in mouse plasma by LC–MS/MS
por: Zeng, Qingyuan, et al.
Publicado: (2022)

Largazole Pharmacokinetics in Rats by LC-MS/MS
por: Yu, Mingming, et al.
Publicado: (2014)

Pharmacological Significance of Heme Oxygenase 1 in Prostate Cancer
por: Ben-Eltriki, Mohamed, et al.
Publicado: (2023)

LC-MS/MS Method for Determination of Hydroxychloroquine and Metabolites: Application in a Pharmacokinetic Study
por: Cui, Lili, et al.
Publicado: (2022)

Determination of tacrolimus in human whole blood in kidney transplant recipients using a rapid and specific LC–MS/MS method
por: Hieu, Tran Ba, et al.
Publicado: (2023)

Visualization of LC‐MS/MS proteomics data in MaxQuant
por: Tyanova, Stefka, et al.
Publicado: (2015)

Simultaneous Determination of Atorvastatin and Aspirin in Human Plasma by LC–MS/MS: Its Pharmacokinetic Application
por: Gajula, Ramakrishna, et al.
Publicado: (2012)

Determination of dihydromyricetin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study
por: Liu, Lu, et al.
Publicado: (2016)

Determination of cepharanthine in rat plasma by LC–MS/MS and its application to a pharmacokinetic study
por: Deng, Yingbin, et al.
Publicado: (2017)

LC–MS/MS determination and pharmacokinetic study of columbianadin in rat plasma after intravenous administration of pure columbianadin
por: Chang, Yan-xu, et al.
Publicado: (2014)

Determination of the Pharmacokinetics and Oral Bioavailability of Salicylamine, a Potent γ-Ketoaldehyde Scavenger, by LC/MS/MS
por: Zagol-Ikapitte, Irene, et al.
Publicado: (2010)

Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application
por: Liu, Yanping, et al.
Publicado: (2013)

Precolumn derivatization LC–MS/MS method for the determination and pharmacokinetic study of glucosamine in human plasma and urine
por: Song, Min, et al.
Publicado: (2012)

Simultaneous determination of amlodipine, valsartan and hydrochlorothiazide by LC–ESI-MS/MS and its application to pharmacokinetics in rats
por: Gadepalli, Shankar Ganesh, et al.
Publicado: (2014)

Validated LC-MS/MS Method for the Determination of Scopoletin in Rat Plasma and Its Application to Pharmacokinetic Studies
por: Zeng, Yingchun, et al.
Publicado: (2015)

Establishment of LC-MS/MS Method for Determination of GMDTC in Rat Plasma and Its Application in Preclinical Pharmacokinetics
por: Hu, Wei, et al.
Publicado: (2023)

Effects of triptolide on pharmacokinetics of amlodipine in rats by using LC–MS/MS
por: Zhang, Chengyin, et al.
Publicado: (2018)

Simultaneous determination of acetaminophen and oxycodone in human plasma by LC–MS/MS and its application to a pharmacokinetic study
por: Lu, Wei, et al.
Publicado: (2018)

Determination of Epimedin B in Rat Plasma and Tissue by LC-MS/MS: Application in Pharmacokinetic and Tissue Distribution Studies
por: Feng, Qianru, et al.
Publicado: (2017)

Evaluation of Stability of Thiopurine Metabolites Using a Validated LC-MS/MS Method
por: Yoo, In-Young, et al.
Publicado: (2018)

Pharmacokinetic Comparisons of Naringenin and Naringenin-Nicotinamide Cocrystal in Rats by LC-MS/MS
por: Xu, Dan, et al.
Publicado: (2020)

Simultaneous determination of telmisartan and amlodipine in human plasma by LC–MS/MS and its application in a human pharmacokinetic study
por: Ravi, Vasu Babu, et al.
Publicado: (2012)

Simultaneous determination of pioglitazone and candesartan in human plasma by LC-MS/MS and its application to a human pharmacokinetic study
por: Kumari Karra, Vijaya, et al.
Publicado: (2012)

A validated LC–MS/MS method for the determination of tolterodine and its metabolite in rat plasma and application to pharmacokinetic study
por: Shaik, Rihana Parveen, et al.
Publicado: (2013)

LC–MS/MS assay for the determination of natamycin in rabbit and human plasma: Application to a pharmacokinetics and protein binding study
por: Chhonker, Yashpal Singh, et al.
Publicado: (2013)

Quantitative determination of D(4)-cystine in mice using LC-MS/MS and its application to the assessment of pharmacokinetics and bioavailability
por: Li, Shuning, et al.
Publicado: (2021)

Development, Validation, and Application of the LC-MS/MS Method for Determination of 4-Acetamidobenzoic Acid in Pharmacokinetic Pilot Studies in Pigs
por: Markowska, Paulina, et al.
Publicado: (2021)

Determination of cefcapene acid by LC–MS and their application to a pharmacokinetic study in healthy Chinese volunteers
por: Duan, Hong-Fei, et al.
Publicado: (2013)

Identification and Pharmacokinetic Studies on Complanatuside and Its Major Metabolites in Rats by UHPLC-Q-TOF-MS/MS and LC-MS/MS
por: Yao, Yu-Feng, et al.
Publicado: (2018)

Analytical Challenges: Determination of Tetrodotoxin in Human Urine and Plasma by LC-MS/MS
por: Leung, Kelvin Sze-Yin, et al.
Publicado: (2011)

A Universal LC-MS/MS Method for Simultaneous Detection of Antibiotic Residues in Animal and Environmental Samples
por: Chan, Chak-Lun, et al.
Publicado: (2022)

Development and validation of a LC–MS/MS method for quantification of hetrombopag for pharmacokinetics study
por: Chen, Tao, et al.
Publicado: (2015)

Quantification of tolvaptan in rabbit plasma by LC–MS/MS: Application to a pharmacokinetic study()
por: Moola, Kumar S., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_h2sd6i9qth5hs2fe4fksuh010d