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Development of Robust Tablet Formulations with Enhanced Drug Dissolution Profiles from Centrifugally-Spun Micro-Fibrous Solid Dispersions of Itraconazole, a BCS Class II Drug

Fibre-based oral drug delivery systems are an attractive approach to addressing low drug solubility, although clear strategies for incorporating such systems into viable dosage forms have not yet been demonstrated. The present study extends our previous work on drug-loaded sucrose microfibres produc...

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Detalles Bibliográficos
Autores principales: Marano, Stefania, Ghimire, Manish, Missaghi, Shahrzad, Rajabi-Siahboomi, Ali, Craig, Duncan Q. M., Barker, Susan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053999/
https://www.ncbi.nlm.nih.gov/pubmed/36986664
http://dx.doi.org/10.3390/pharmaceutics15030802