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The Mechanisms of GPR55 Receptor Functional Selectivity during Apoptosis and Proliferation Regulation in Cancer Cells

GPR55 is a non-canonical cannabinoid receptor, important for cancer proliferation. Depending on the ligand, it induces either cell proliferation or death. The objective of the study was to establish the mechanisms of this multidirectional signaling. Using the CRISPR-Cas9 system, the GPR55, CB1, CB2,...

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Detalles Bibliográficos
Autores principales: Akimov, Mikhail G., Gretskaya, Natalia M., Dudina, Polina V., Sherstyanykh, Galina D., Zinchenko, Galina N., Serova, Oksana V., Degtyaryova, Ksenia O., Deyev, Igor E., Bezuglov, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054013/
https://www.ncbi.nlm.nih.gov/pubmed/36982628
http://dx.doi.org/10.3390/ijms24065524