Oligonucleotide Formulations Prepared by High-Speed Electrospinning: Maximizing Loading and Exploring Downstream Processability

The aim of this study was to develop antisense oligonucleotide tablet formulations using high-speed electrospinning. Hydroxypropyl-beta-cyclodextrin (HPβCD) was used as a stabilizer and as an electrospinning matrix. In order to optimize the morphology of the fibers, electrospinning of various formul...

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Detalles Bibliográficos
Autores principales: Hirsch, Edit, Nacsa, Márió, Pantea, Eszter, Szabó, Edina, Vass, Panna, Domján, Júlia, Farkas, Attila, Nyíri, Zoltán, Eke, Zsuzsanna, Vigh, Tamás, Andersen, Sune Klint, Verreck, Geert, Marosi, György János, Nagy, Zsombor Kristóf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054037/
https://www.ncbi.nlm.nih.gov/pubmed/36986716
http://dx.doi.org/10.3390/pharmaceutics15030855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054037/
https://www.ncbi.nlm.nih.gov/pubmed/36986716
http://dx.doi.org/10.3390/pharmaceutics15030855

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