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Novel Steroidal[17,16-d]pyrimidines Derived from Epiandrosterone and Androsterone: Synthesis, Characterization and Configuration-Activity Relationships

Two series of novel steroidal[17,16-d]pyrimidines derived from natural epiandrosterone and androsterone were designed and synthesized, and these compounds were screened for their potential anticancer activities. The preliminary bioassay indicated that some of these prepared compounds exhibited signi...

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Detalles Bibliográficos
Autores principales: Yang, Fei, Liu, Fang, Min, Yong, Shi, Liqiao, Liu, Manli, Wang, Kaimei, Ke, Shaoyong, Gong, Yan, Yang, Ziwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054084/
https://www.ncbi.nlm.nih.gov/pubmed/36985662
http://dx.doi.org/10.3390/molecules28062691