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Maleic Acid as a Co-Former for Pharmaceutically Active GABA Derivatives: Mechanochemistry or Solvent Crystallization?

In this study, we compare the mechanochemical and classical solvent crystallization methods for forming maleates of GABA and its pharmaceutically active derivatives: Pregabalin, Gabapentin, Phenibut, and Baclofen. Common characterization techniques, like powder and single crystal X-ray diffraction,...

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Detalles Bibliográficos
Autores principales: Komisarek, Daniel, Taskiran, Ebru, Vasylyeva, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054091/
https://www.ncbi.nlm.nih.gov/pubmed/36984121
http://dx.doi.org/10.3390/ma16062242