Fibrillin-1 mutation contributes to Marfan syndrome by inhibiting Cav1.2-mediated cell proliferation in vascular smooth muscle cells

Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder caused by mutation in fibrillin-1 (FBN1). However, the molecular mechanism underlying MFS remains poorly understood. The study aimed to explore how the L-type calcium channel (Ca(V)1.2) modulates disease progression of MFS and...

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Detalles Bibliográficos
Autores principales: Lin, Wenfeng, Xiong, Jiaqi, Jiang, Yefan, Liu, Hao, Bian, Jinhui, Wang, Juejin, Shao, Yongfeng, Ni, Buqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054150/
https://www.ncbi.nlm.nih.gov/pubmed/36972239
http://dx.doi.org/10.1080/19336950.2023.2192377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054150/
https://www.ncbi.nlm.nih.gov/pubmed/36972239
http://dx.doi.org/10.1080/19336950.2023.2192377

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