Deficiency of lipopolysaccharide binding protein facilitates adipose browning, glucose uptake and oxygen consumption in mouse embryonic fibroblasts via activating PI3K/Akt/mTOR pathway and inhibiting autophagy

This study aimed to explore the role of lipopolysaccharide-binding protein (LBP) in adipose browning. Mouse embryonic fibroblasts (MEFs) were treated with differentiation induction reagents and Perifosine (Akt inhibitor), with the transfection of Atg5, short hairpin RNA targeting LBP (shLBP), and At...

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Detalles Bibliográficos
Autores principales: Yin, Xueyao, Xu, Zhiye, Zhang, Xinxin, Wu, Jiahua, Lu, Weina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054173/
https://www.ncbi.nlm.nih.gov/pubmed/36710409
http://dx.doi.org/10.1080/15384101.2023.2169521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054173/
https://www.ncbi.nlm.nih.gov/pubmed/36710409
http://dx.doi.org/10.1080/15384101.2023.2169521

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