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Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model

Shiga toxins (Stxs) produced by ingested E. coli can induce hemolytic uremic syndrome after crossing the intact intestinal barrier, entering the bloodstream, and targeting endothelial cells in the kidney. The method(s) by which the toxins reach the bloodstream are not fully defined. Here, we used tw...

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Detalles Bibliográficos
Autores principales: Bova, Rebecca A., Lamont, Andrew C., Picou, Theodore J., Ho, Vincent B., Gilchrist, Kristin H., Melton-Celsa, Angela R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054274/
https://www.ncbi.nlm.nih.gov/pubmed/36977098
http://dx.doi.org/10.3390/toxins15030207