Cargando…

The Influence of Protein Charge and Molecular Weight on the Affinity of Aptamers

Aptamers offer several advantages over antibodies. However, to ensure high affinity and specificity, a better understanding of the interactions between the nucleic-acid-based aptamers and their targets is mandatory. Therefore, we investigated the influence of two physical properties of proteins—mole...

Descripción completa

Detalles Bibliográficos
Autores principales: Drees, Alissa, Trinh, Tung Lam, Fischer, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054347/
https://www.ncbi.nlm.nih.gov/pubmed/36986556
http://dx.doi.org/10.3390/ph16030457