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The Influence of Protein Charge and Molecular Weight on the Affinity of Aptamers
Aptamers offer several advantages over antibodies. However, to ensure high affinity and specificity, a better understanding of the interactions between the nucleic-acid-based aptamers and their targets is mandatory. Therefore, we investigated the influence of two physical properties of proteins—mole...
Autores principales: | Drees, Alissa, Trinh, Tung Lam, Fischer, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054347/ https://www.ncbi.nlm.nih.gov/pubmed/36986556 http://dx.doi.org/10.3390/ph16030457 |
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