Turning a Tumor Microenvironment Pitfall into Opportunity: Discovery of Benzamidoxime as PD-L1 Ligand with pH-Dependent Potency

PD-1/PD-L1 protein complex is attracting a great deal of interest as a drug target for the design of immune therapies able to block its assembly. Although some biologic drugs have entered clinical use, their poor response rate in patients are demanding further efforts to design small molecule inhibi...

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Detalles Bibliográficos
Autores principales: Bianconi, Elisa, Riccio, Alessandra, Ruta, Luana, Bigiotti, Carlo, Carotti, Andrea, Moretti, Sonia, Cerra, Bruno, Gioiello, Antimo, Ferlin, Simone, Puxeddu, Efisio, Macchiarulo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054428/
https://www.ncbi.nlm.nih.gov/pubmed/36982608
http://dx.doi.org/10.3390/ijms24065535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054428/
https://www.ncbi.nlm.nih.gov/pubmed/36982608
http://dx.doi.org/10.3390/ijms24065535

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