Design, Synthesis, and Biological Evaluation of Sulfonamide Methoxypyridine Derivatives as Novel PI3K/mTOR Dual Inhibitors

Phosphatidylinositol 3-kinase (PI3K) plays an important role in cell proliferation, survival, migration, and metabolism, and has become an effective target for cancer treatment. Meanwhile, inhibiting both PI3K and mammalian rapamycin receptor (mTOR) can simultaneously improve the efficiency of anti-...

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Detalles Bibliográficos
Autores principales: Gao, Haotian, Li, Zaolin, Wang, Kai, Zhang, Yuhan, Wang, Tong, Wang, Fang, Xu, Youjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054477/
https://www.ncbi.nlm.nih.gov/pubmed/36986560
http://dx.doi.org/10.3390/ph16030461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054477/
https://www.ncbi.nlm.nih.gov/pubmed/36986560
http://dx.doi.org/10.3390/ph16030461

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