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GSK3β Inhibition Reduced Vascular Calcification in Ins2(Akita/+) Mice

Endothelial–mesenchymal transition (EndMT) drives the endothelium to contribute to vascular calcification in diabetes mellitus. In our previous study, we showed that glycogen synthase kinase-3β (GSK3β) inhibition induces β-catenin and reduces mothers against DPP homolog 1 (SMAD1) to direct osteoblas...

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Detalles Bibliográficos
Autores principales: Boström, Kristina I., Qiao, Xiaojing, Zhao, Yan, Wu, Xiuju, Zhang, Li, Ma, Jocelyn A., Ji, Jaden, Cai, Xinjiang, Yao, Yucheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054481/
https://www.ncbi.nlm.nih.gov/pubmed/36983045
http://dx.doi.org/10.3390/ijms24065971