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A Molecular Docking Study Reveals That Short Peptides Induce Conformational Changes in the Structure of Human Tubulin Isotypes αβI, αβII, αβIII and αβIV

Microtubules are cylindrical protein polymers assembled in the cytoplasm of all eukaryotic cells by polymerization of aβ tubulin dimers, which are involved in cell division, migration, signaling, and intracellular traffic. These functions make them essential in the proliferation of cancerous cells a...

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Detalles Bibliográficos
Autores principales: Ebenezer, Oluwakemi, Damoyi, Nkululeko, Shapi, Michael, Wong, Gane Ka-Shu, Tuszynski, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054586/
https://www.ncbi.nlm.nih.gov/pubmed/36976059
http://dx.doi.org/10.3390/jfb14030135