Phenotyping Indices of CYP450 and P-Glycoprotein in Human Volunteers and in Patients Treated with Painkillers or Psychotropic Drugs

Drug-metabolizing enzymes and drug transporters are key determinants of drug pharmacokinetics and response. The cocktail-based cytochrome P450 (CYP) and drug transporter phenotyping approach consists in the administration of multiple CYP or transporter-specific probe drugs to determine their activit...

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Detalles Bibliográficos
Autores principales: Darnaud, Léa, Delage, Clément, Daali, Youssef, Trouvin, Anne-Priscille, Perrot, Serge, Khoudour, Nihel, Merise, Nadia, Labat, Laurence, Etain, Bruno, Bellivier, Frank, Lloret-Linares, Célia, Bloch, Vanessa, Curis, Emmanuel, Declèves, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054647/
https://www.ncbi.nlm.nih.gov/pubmed/36986840
http://dx.doi.org/10.3390/pharmaceutics15030979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054647/
https://www.ncbi.nlm.nih.gov/pubmed/36986840
http://dx.doi.org/10.3390/pharmaceutics15030979

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