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A Review of Quantitative Systems Pharmacology Models of the Coagulation Cascade: Opportunities for Improved Usability

Despite the numerous therapeutic options to treat bleeding or thrombosis, a comprehensive quantitative mechanistic understanding of the effects of these and potential novel therapies is lacking. Recently, the quality of quantitative systems pharmacology (QSP) models of the coagulation cascade has im...

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Detalles Bibliográficos
Autores principales: Chung, Douglas, Bakshi, Suruchi, van der Graaf, Piet H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054658/
https://www.ncbi.nlm.nih.gov/pubmed/36986779
http://dx.doi.org/10.3390/pharmaceutics15030918