Neuroprotective Effects of the Neural-Induced Adipose-Derived Stem Cell Secretome against Rotenone-Induced Mitochondrial and Endoplasmic Reticulum Dysfunction

Mesenchymal stem cells (MSCs) have therapeutic effects on neurodegenerative diseases (NDDs) known by their secreted molecules, referred to as the “secretome”. The mitochondrial complex I inhibitor, rotenone (ROT), reproduces α-synuclein (α-syn) aggregation seen in Parkinson’s disease (PD). In this p...

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Detalles Bibliográficos
Autores principales: Ramalingam, Mahesh, Jang, Sujeong, Hwang, Jinsu, Kim, Boeun, Cho, Hyong-Ho, Kim, Eungpil, Jeong, Han-Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054666/
https://www.ncbi.nlm.nih.gov/pubmed/36982698
http://dx.doi.org/10.3390/ijms24065622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054666/
https://www.ncbi.nlm.nih.gov/pubmed/36982698
http://dx.doi.org/10.3390/ijms24065622

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