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Neuroprotective Effects of the Neural-Induced Adipose-Derived Stem Cell Secretome against Rotenone-Induced Mitochondrial and Endoplasmic Reticulum Dysfunction
Mesenchymal stem cells (MSCs) have therapeutic effects on neurodegenerative diseases (NDDs) known by their secreted molecules, referred to as the “secretome”. The mitochondrial complex I inhibitor, rotenone (ROT), reproduces α-synuclein (α-syn) aggregation seen in Parkinson’s disease (PD). In this p...
Autores principales: | Ramalingam, Mahesh, Jang, Sujeong, Hwang, Jinsu, Kim, Boeun, Cho, Hyong-Ho, Kim, Eungpil, Jeong, Han-Seong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054666/ https://www.ncbi.nlm.nih.gov/pubmed/36982698 http://dx.doi.org/10.3390/ijms24065622 |
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