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Strain-Specific Interactions between the Viral Capsid Proteins VP4, VP7 and VP6 Influence Rescue of Rotavirus Reassortants by Reverse Genetics

Rotavirus A (RVA) genome segments can reassort upon co-infection of target cells with two different RVA strains. However, not all reassortants are viable, which limits the ability to generate customized viruses for basic and applied research. To gain insight into the factors that restrict reassortme...

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Detalles Bibliográficos
Autores principales: Valusenko-Mehrkens, Roman, Gadicherla, Ashish K., Johne, Reimar, Falkenhagen, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054668/
https://www.ncbi.nlm.nih.gov/pubmed/36982745
http://dx.doi.org/10.3390/ijms24065670