A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewis(x) Mimetics

The d-GlcNAc moiety in sialyl Lewis(x) (sLe(x), 1) acts predominantly as a linker to position the d-Gal and the l-Fuc moieties in the bioactive spatial orientation. The hypothesis has been made that the NHAc group of GlcNAc pushes the fucose underneath the galactose and, thus, contributes to the sta...

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Detalles Bibliográficos
Autores principales: Wagner, Beatrice, Binder, Florian P. C., Jiang, Xiaohua, Mühlethaler, Tobias, Preston, Roland C., Rabbani, Said, Smieško, Martin, Schwardt, Oliver, Ernst, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054758/
https://www.ncbi.nlm.nih.gov/pubmed/36985569
http://dx.doi.org/10.3390/molecules28062595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054758/
https://www.ncbi.nlm.nih.gov/pubmed/36985569
http://dx.doi.org/10.3390/molecules28062595

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