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SGLT2 Inhibitor—Dapagliflozin Attenuates Diabetes-Induced Renal Injury by Regulating Inflammation through a CYP4A/20-HETE Signaling Mechanism

Diabetic kidney disease (DKD) is a serious complication of diabetes, affecting millions of people worldwide. Inflammation and oxidative stress are key contributors to the development and progression of DKD, making them potential targets for therapeutic interventions. Sodium-glucose cotransporter 2 i...

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Detalles Bibliográficos
Autores principales: Dia, Batoul, Alkhansa, Sahar, Njeim, Rachel, Al Moussawi, Sarah, Farhat, Theresa, Haddad, Antony, Riachi, Mansour E., Nawfal, Rashad, Azar, William S., Eid, Assaad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054805/
https://www.ncbi.nlm.nih.gov/pubmed/36986825
http://dx.doi.org/10.3390/pharmaceutics15030965