Immunogenicity of COVID-eVax Delivered by Electroporation Is Moderately Impacted by Temperature and Molecular Isoforms

DNA integrity is a key issue in gene therapy and genetic vaccine approaches based on plasmid DNA. In contrast to messenger RNA that requires a controlled cold chain for efficacy, DNA molecules are considered to be more stable. In this study, we challenged this concept by characterizing the immunolog...

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Detalles Bibliográficos
Autores principales: D’Alessio, Federico, Lione, Lucia, Salvatori, Erika, Bucci, Federica, Muzi, Alessia, Roscilli, Giuseppe, Compagnone, Mirco, Pinto, Eleonora, Battistuzzi, Gianfranco, Conforti, Antonella, Aurisicchio, Luigi, Palombo, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054807/
https://www.ncbi.nlm.nih.gov/pubmed/36992261
http://dx.doi.org/10.3390/vaccines11030678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054807/
https://www.ncbi.nlm.nih.gov/pubmed/36992261
http://dx.doi.org/10.3390/vaccines11030678

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