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CochleRob: Parallel-Serial Robot to Position a Magnetic Actuator around a Patient’s Head for Intracochlear Microrobot Navigation

Our work introduces a new robotic solution named CochleRob, which is used for the administration of super-paramagnetic antiparticles as drug carriers into the human cochlea for the treatment of hearing loss caused by damaged cochlea. This novel robot architecture presents two key contributions. Firs...

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Detalles Bibliográficos
Autores principales: Nadour, Housseyne, Bozorg Grayeli, Alexis, Poisson, Gérard, Belharet, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054852/
https://www.ncbi.nlm.nih.gov/pubmed/36991684
http://dx.doi.org/10.3390/s23062973
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author Nadour, Housseyne
Bozorg Grayeli, Alexis
Poisson, Gérard
Belharet, Karim
author_facet Nadour, Housseyne
Bozorg Grayeli, Alexis
Poisson, Gérard
Belharet, Karim
author_sort Nadour, Housseyne
collection PubMed
description Our work introduces a new robotic solution named CochleRob, which is used for the administration of super-paramagnetic antiparticles as drug carriers into the human cochlea for the treatment of hearing loss caused by damaged cochlea. This novel robot architecture presents two key contributions. First, CochleRob has been designed to meet specifications pertaining to ear anatomy, including workspace, degrees of freedom, compactness, rigidity, and accuracy. The first objective was to develop a safer mathod to administer drugs to the cochlea without the need for catheter or CI insertion. Secondly, we aimed at developing and validating the mathemathical models, including forward, inverse, and dynamic models, to support the robot function. Our work provides a promising solution for drug administration into the inner ear.
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spelling pubmed-100548522023-03-30 CochleRob: Parallel-Serial Robot to Position a Magnetic Actuator around a Patient’s Head for Intracochlear Microrobot Navigation Nadour, Housseyne Bozorg Grayeli, Alexis Poisson, Gérard Belharet, Karim Sensors (Basel) Article Our work introduces a new robotic solution named CochleRob, which is used for the administration of super-paramagnetic antiparticles as drug carriers into the human cochlea for the treatment of hearing loss caused by damaged cochlea. This novel robot architecture presents two key contributions. First, CochleRob has been designed to meet specifications pertaining to ear anatomy, including workspace, degrees of freedom, compactness, rigidity, and accuracy. The first objective was to develop a safer mathod to administer drugs to the cochlea without the need for catheter or CI insertion. Secondly, we aimed at developing and validating the mathemathical models, including forward, inverse, and dynamic models, to support the robot function. Our work provides a promising solution for drug administration into the inner ear. MDPI 2023-03-09 /pmc/articles/PMC10054852/ /pubmed/36991684 http://dx.doi.org/10.3390/s23062973 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nadour, Housseyne
Bozorg Grayeli, Alexis
Poisson, Gérard
Belharet, Karim
CochleRob: Parallel-Serial Robot to Position a Magnetic Actuator around a Patient’s Head for Intracochlear Microrobot Navigation
title CochleRob: Parallel-Serial Robot to Position a Magnetic Actuator around a Patient’s Head for Intracochlear Microrobot Navigation
title_full CochleRob: Parallel-Serial Robot to Position a Magnetic Actuator around a Patient’s Head for Intracochlear Microrobot Navigation
title_fullStr CochleRob: Parallel-Serial Robot to Position a Magnetic Actuator around a Patient’s Head for Intracochlear Microrobot Navigation
title_full_unstemmed CochleRob: Parallel-Serial Robot to Position a Magnetic Actuator around a Patient’s Head for Intracochlear Microrobot Navigation
title_short CochleRob: Parallel-Serial Robot to Position a Magnetic Actuator around a Patient’s Head for Intracochlear Microrobot Navigation
title_sort cochlerob: parallel-serial robot to position a magnetic actuator around a patient’s head for intracochlear microrobot navigation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054852/
https://www.ncbi.nlm.nih.gov/pubmed/36991684
http://dx.doi.org/10.3390/s23062973
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