Prediction of the Drug–Drug Interaction Potential between Tegoprazan and Amoxicillin/Clarithromycin Using the Physiologically Based Pharmacokinetic and Pharmacodynamic Model

Tegoprazan is a novel potassium-competitive acid blocker. This study investigated the effect of drug–drug interaction on the pharmacokinetics and pharmacodynamics of tegoprazan co-administered with amoxicillin and clarithromycin, the first-line therapy for the eradication of Helicobacter pylori, usi...

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Detalles Bibliográficos
Autores principales: Wei, Zhuodu, Jeong, Hyeon-Cheol, Kim, Min-Gul, Shin, Kwang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054914/
https://www.ncbi.nlm.nih.gov/pubmed/36986460
http://dx.doi.org/10.3390/ph16030360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054914/
https://www.ncbi.nlm.nih.gov/pubmed/36986460
http://dx.doi.org/10.3390/ph16030360

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