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Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data

Sample-wise deconvolution methods have been developed to estimate cell-type proportions and gene expressions in bulk-tissue samples. However, the performance of these methods and their biological applications has not been evaluated, particularly on human brain transcriptomic data. Here, nine deconvo...

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Detalles Bibliográficos
Autores principales: Dai, Rujia, Chu, Tianyao, Zhang, Ming, Wang, Xuan, Jourdon, Alexandre, Wu, Feinan, Mariani, Jessica, Vaccarino, Flora M., Lee, Donghoon, Fullard, John F., Hoffman, Gabriel E., Roussos, Panos, Wang, Yue, Wang, Xusheng, Pinto, Dalila, Wang, Sidney H., Zhang, Chunling, Chen, Chao, Liu, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054947/
https://www.ncbi.nlm.nih.gov/pubmed/36993743
http://dx.doi.org/10.1101/2023.03.13.532468