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30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC

Acquired ribosomal RNA (rRNA) methylation has emerged as a significant mechanism of aminoglycoside resistance in pathogenic bacterial infections. Modification of a single nucleotide in the ribosome decoding center by the aminoglycoside-resistance 16S rRNA (m(7)G1405) methyltransferases effectively b...

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Detalles Bibliográficos
Autores principales: Srinivas, Pooja, Nosrati, Meisam, Zelinskaya, Natalia, Dey, Debayan, Comstock, Lindsay R., Dunham, Christine M., Conn, Graeme L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054953/
https://www.ncbi.nlm.nih.gov/pubmed/36993224
http://dx.doi.org/10.1101/2023.03.13.532395