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30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC
Acquired ribosomal RNA (rRNA) methylation has emerged as a significant mechanism of aminoglycoside resistance in pathogenic bacterial infections. Modification of a single nucleotide in the ribosome decoding center by the aminoglycoside-resistance 16S rRNA (m(7)G1405) methyltransferases effectively b...
Autores principales: | Srinivas, Pooja, Nosrati, Meisam, Zelinskaya, Natalia, Dey, Debayan, Comstock, Lindsay R., Dunham, Christine M., Conn, Graeme L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054953/ https://www.ncbi.nlm.nih.gov/pubmed/36993224 http://dx.doi.org/10.1101/2023.03.13.532395 |
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