Cristae formation is a mechanical buckling event controlled by the inner membrane lipidome

Cristae are high curvature structures in the inner mitochondrial membrane (IMM) that are crucial for ATP production. While cristae-shaping proteins have been defined, analogous mechanisms for lipids have yet to be elucidated. Here we combine experimental lipidome dissection with multi-scale modeling...

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Detalles Bibliográficos
Autores principales: Venkatraman, Kailash, Lee, Christopher T., Garcia, Guadalupe C., Mahapatra, Arijit, Milshteyn, Daniel, Perkins, Guy, Kim, Keun-Young, Pasolli, H. Amalia, Phan, Sebastien, Lippincott-Schwartz, Jennifer, Ellisman, Mark H., Rangamani, Padmini, Budin, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054968/
https://www.ncbi.nlm.nih.gov/pubmed/36993370
http://dx.doi.org/10.1101/2023.03.13.532310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054968/
https://www.ncbi.nlm.nih.gov/pubmed/36993370
http://dx.doi.org/10.1101/2023.03.13.532310

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